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Article

The SNF1 Kinase Ubiquitin-associated Domain Restrains Its Activation, Activity, and the Yeast Life Span.

The Journal of biological chemistry - 19 Jun 2015

Jiao Rubin, Postnikoff Spike, Harkness Troy A, Arnason Terra G

Abstract excerpt

The enzyme family of heterotrimeric AMP-dependent protein kinases is activated upon low energy states, conferring a switch toward energy-conserving metabolic pathways through immediate kinase actions on enzyme targets and delayed alterations in gene expression through its nuclear relocalization. This family is evolutionarily conserved, including the presence of a ubiquitin-associated (UBA) motif in most catalytic...

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Identifiers

PMID: 25869125
DOI: 10.1074/jbc.M115.647032
PMCID: PMC4505455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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