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Article

Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.

Proceedings of the National Academy of Sciences of the United States of America - 10 Feb 2009

Carneiro Ana M D, Airey David C, Thompson Brent, Zhu Chong-Bin, Lu Lu, Chesler Elissa J, Erikson Keith M, Blakely Randy D

Abstract excerpt

The human serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT, SLC6A4) figures prominently in the etiology and treatment of many prevalent neurobehavioral disorders including anxiety, alcoholism, depression, autism, and obsessive-compulsive disorder (OCD). Here, we use naturally occurring polymorphisms in recombinant inbred (RI) lines to identify multiple phenotypes associated with altered SERT function. The...

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Identifiers

PMID: 19179283
DOI: 10.1073/pnas.0809449106
PMCID: PMC2632716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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