Article
An organic acid based counter selection system for cyanobacteria.
PloS one - 1 Jan 2013
Begemann Matthew B, Zess Erin K, Walters Eric M, Schmitt Emily F, Markley Andrew L, Pfleger Brian F
Abstract excerpt
Cyanobacteria are valuable organisms for studying the physiology of photosynthesis and carbon fixation, as well as metabolic engineering for the production of fuels and chemicals. This work describes a novel counter selection method for the cyanobacterium Synechococcus sp. PCC 7002 based on organic acid toxicity. The organic acids acrylate, 3-hydroxypropionate, and propionate were shown to be inhibitory towards...
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