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Pioneering precision in markerless strain development for Synechococcus sp. PCC 7002.

Microbial cell factories - 8 Oct 2024

Tsuji Ayaka, Inabe Kosuke, Hidese Ryota, Kato Yuichi, Domingues Lucília, Kondo Akihiko, Hasunuma Tomohisa

Abstract excerpt

Marine cyanobacteria such as Picosynechococcus sp. (formerly called Synechococcus sp.) PCC 7002 are promising chassis for photosynthetic production of commodity chemicals with low environmental burdens. Genetic engineering of cyanobacteria conventionally employs antibiotic resistance markers. However, limited availability of antibiotic-resistant markers is a problem for highly multigenic strain engineering....

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Bacterial Proteins
Escherichia coli
Genetic Engineering
Mutation
Synechococcus

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PMID: 39379966
DOI: 10.1186/s12934-024-02543-6
PMCID: PMC11462663

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