High hepatitis B virus surface antigen levels and favorable interleukin 28B genotype predict spontaneous hepatitis C virus clearance in uremic patients.

doi:10.1016/j.jhep.2013.09.023

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Article

High hepatitis B virus surface antigen levels and favorable interleukin 28B genotype predict spontaneous hepatitis C virus clearance in uremic patients.

Journal of hepatology - 1 Feb 2014

Yu Ming-Lung, Dai Chia-Yen, Huang Chung-Feng, Lee Jia-Jung, Yeh Ming-Lun, Yeh Shih-Meng, Kuo Hsing-Tao, Huang Jee-Fu, Chang Jer-Ming, Chen Hung-Chun, Juo Suh-Hang Hank, Hwang Shang-Jyh, Chuang Wan-Long

Abstract excerpt

BACKGROUND & AIMS: Host and viral factors interplay in the spontaneous clearance of hepatitis C virus (HCV) infection. We aimed to explore the roles of IL28B genotypes and hepatitis B virus (HBV) infections in spontaneous HCV seroclearance. METHODS: IL28B rs8099917 genotypes, HCV and HBV markers were determined in 290 patients who were seropositive for HCV antibodies from 1681 total uremic patients on maintenance...

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PMID: 24096049
DOI: 10.1016/j.jhep.2013.09.023

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