Article
Short communication: Does interleukin-28B single nucleotide polymorphisms influence the natural history of hepatitis B?
AIDS research and human retroviruses - 1 Oct 2012
Martín-Carbonero Luz, Rallón Norma I, Benito José M, Poveda Eva, González-Lahoz Juan, Soriano Vincent
Abstract excerpt
Single nucleotide polymorphisms (SNP) nearby the IL28B gene have been associated with spontaneous hepatitis C virus (HCV) clearance and response to interferon-based therapies in both monoinfected and HIV-coinfected patients. However, its impact on spontaneous clearance of HBV (the pathogenesis of which is also related to interferon) is less known. A case-control study was performed. Cases were 49 HIV(+) patients...
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