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Article

A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice.

Gastroenterology - 1 Nov 2010

Tillmann Hans L, Thompson Alex J, Patel Keyur, Wiese Manfred, Tenckhoff Hannelore, Nischalke Hans D, Lokhnygina Yuliya, Kullig Ulrike, Göbel Uwe, Capka Emanuela, Wiegand Johannes, Schiefke Ingolf, Güthoff Wolfgang, Grüngreiff Kurt, König Ingrid, Spengler Ulrich, McCarthy Jeanette, Shianna Kevin V, Goldstein David B, McHutchison John G, Timm Jörg, Nattermann Jacob

Abstract excerpt

BACKGROUND & AIMS: A single nucleotide polymorphism (SNP) upstream of the IL28B gene has been associated with response of patients with chronic hepatitis C to therapy with pegylated interferon and ribavirin and also with spontaneous clearance of acute hepatitis C in a heterogeneous population. We analyzed the association between IL28B and the clinical presentation of acute hepatitis C virus (HCV) infection in a...

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Identifiers

PMID: 20637200
DOI: 10.1053/j.gastro.2010.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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