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Article

Association between IL28B polymorphisms and spontaneous clearance of hepatitis B virus infection.

PloS one - 1 Jan 2013

Kim Seung Up, Song Ki Jun, Chang Hye Young, Shin Eui-Cheol, Park Jun Yong, Kim Do Young, Han Kwang-Hyub, Chon Chae Yoon, Ahn Sang Hoon

Abstract excerpt

BACKGROUND/AIMS: Single-nucleotide polymorphisms (SNPs) near the interleukin 28B gene (IL28B; interferon [IFN]-λ-3) are associated with outcomes of chronic hepatitis C virus (HCV) and hepatitis B virus (HBV) infection treated with peginterferon (PEG-IFN) alpha-based antiviral therapy. In this study, we investigated the influence of IL28B polymorphisms on spontaneous clearance of HBV infection in a large Korean...

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Identifiers

PMID: 23874902
DOI: 10.1371/journal.pone.0069166
PMCID: PMC3714234

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