The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection.

doi:10.1002/hep.26639

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Article

The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection.

Hepatology (Baltimore, Md.) - 1 Jan 2014

Grebely Jason, Page Kimberly, Sacks-Davis Rachel, van der Loeff Maarten Schim, Rice Thomas M, Bruneau Julie, Morris Meghan D, Hajarizadeh Behzad, Amin Janaki, Cox Andrea L, Kim Arthur Y, McGovern Barbara H, Schinkel Janke, George Jacob, Shoukry Naglaa H, Lauer Georg M, Maher Lisa, Lloyd Andrew R, Hellard Margaret, Dore Gregory J, Prins Maria

Abstract excerpt

UNLABELLED: Although 20%-40% of persons with acute hepatitis C virus (HCV) infection demonstrate spontaneous clearance, the time course and factors associated with clearance remain poorly understood. We investigated the time to spontaneous clearance and predictors among participants with acute HCV using Cox proportional hazards analyses. Data for this analysis were drawn from an international collaboration of...

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PMID: 23908124
DOI: 10.1002/hep.26639
PMCID: PMC3972017

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