Article
The haplotype assembly model with genotype information and iterative local-exhaustive search algorithm.
Computational biology and chemistry - 1 Aug 2007
Wang Ying, Feng Enmin, Wang Ruisheng, Zhang Dan
Abstract excerpt
The minimum error correction (MEC) model for haplotype reconstruction is efficient only when the error rate in SNP fragments is low. In order to improve reconstruction rate, additional genotype information is added into MEC model as an extension to MEC model. In this paper, we first establish a new mathematical model for haplotype assembly problem with genotype information. Several properties of the mathematical...
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