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Article

A DNA element regulates drug tolerance and withdrawal in Drosophila.

PloS one - 1 Jan 2013

Li Xiaolei, Ghezzi Alfredo, Pohl Jascha B, Bohm Arun Y, Atkinson Nigel S

Abstract excerpt

Drug tolerance and withdrawal are insidious responses to drugs of abuse; the first increases drug consumption while the second punishes abstention. Drosophila generate functional tolerance to benzyl alcohol sedation by increasing neural expression of the slo BK-type Ca(2+) activated K(+) channel...

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Identifiers

PMID: 24086565
DOI: 10.1371/journal.pone.0075549
PMCID: PMC3781064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24086565-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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