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Article

The Esg Gene Is Involved in Nicotine Sensitivity in Drosophila melanogaster.

PloS one - 1 Jan 2015

Sanchez-Díaz Iván, Rosales-Bravo Fernando, Reyes-Taboada José Luis, Covarrubias Alejandra A, Narvaez-Padilla Verónica, Reynaud Enrique

Abstract excerpt

In humans, there is a strong correlation between sensitivity to substances of abuse and addiction risk. This differential tolerance to drugs has a strong genetic component. The identification of human genetic factors that alter drug tolerance has been a difficult task. For this reason and taking advantage of the fact that Drosophila responds similarly to humans to many drugs, and that genetically it has a high...

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Identifiers

PMID: 26222315
DOI: 10.1371/journal.pone.0133956
PMCID: PMC4519288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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