The Esg Gene Is Involved in Nicotine Sensitivity in Drosophila melanogaster.

doi:10.1371/journal.pone.0133956

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Article

The Esg Gene Is Involved in Nicotine Sensitivity in Drosophila melanogaster.

PloS one - 1 Jan 2015

Sanchez-Díaz Iván, Rosales-Bravo Fernando, Reyes-Taboada José Luis, Covarrubias Alejandra A, Narvaez-Padilla Verónica, Reynaud Enrique

Abstract excerpt

In humans, there is a strong correlation between sensitivity to substances of abuse and addiction risk. This differential tolerance to drugs has a strong genetic component. The identification of human genetic factors that alter drug tolerance has been a difficult task. For this reason and taking advantage of the fact that Drosophila responds similarly to humans to many drugs, and that genetically it has a high...

Topics

Alleles
Animals
Base Sequence
Behavior, Animal
Drosophila Proteins
Drosophila melanogaster
Gene Expression Regulation
Gene Knockdown Techniques
Male
MicroRNAs
Mutagenesis, Insertional
Nicotine
Phenotype
Transcription Factors

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Identifiers

PMID: 26222315
DOI: 10.1371/journal.pone.0133956
PMCID: PMC4519288

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