Article
The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila.
Cell metabolism - 1 Jul 2006
King-Jones Kirst, Horner Michael A, Lam Geanette, Thummel Carl S
Abstract excerpt
Exposure to xenobiotics such as plant toxins, pollutants, or prescription drugs triggers a defense response, inducing genes that encode key detoxification enzymes. Although xenobiotic responses have been studied in vertebrates, little effort has been made to exploit a simple genetic system for characterizing the molecular basis of this coordinated transcriptional response. We show here that approximately 1000...
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