Article
The Drosophila homolog of jwa is required for ethanol tolerance.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Li Chunping, Zhao Xiaojia, Cao Xingjiang, Chu Dandan, Chen Jiong, Zhou Jianwei
Abstract excerpt
AIMS: Alcohol abuse poses a serious public health problem, and repeated ingestion can produce tolerance, leading to dependence and addiction. However, the mechanisms underlying alcohol tolerance and addiction are not fully understood. Drosophilae have been employed as a suitable model to study the molecular mechanisms underlying ethanol tolerance. JWA, a newly identified microtubule-binding protein, was shown to...
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