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Article

Genetic variants of coagulation factor XI show association with ischemic stroke up to 70 years of age.

PloS one - 1 Jan 2013

Hanson Ellen, Nilsson Staffan, Jood Katarina, Norrving Bo, Engström Gunnar, Blomstrand Christian, Lindgren Arne, Melander Olle, Jern Christina

Abstract excerpt

BACKGROUND AND PURPOSE: Coagulation factor XI (FXI) has an important role in the propagation and stabilization of a thrombus upon vessel injury. High FXI levels have been implicated in thrombotic diseases including ischemic stroke. The aim of our study was to investigate whether FXI gene (F11) variants are associated with ischemic stroke. METHODS: The discovery sample, the Sahlgrenska Academy Study on Ischemic...

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PMID: 24086496
DOI: 10.1371/journal.pone.0075286
PMCID: PMC3783404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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