Article
Factor XIII A subunit Val34Leu polymorphism in patients suffering atherothrombotic ischemic stroke.
Thrombosis research - 1 Aug 2010
Shemirani Amir H, Pongrácz Endre, Antalfi Bálint, Adány Róza, Muszbek László
Abstract excerpt
INTRODUCTION: Factor XIII (FXIII) is a key regulator of fibrinolysis and clot firmness. Val34Leu polymorphism of its potentially active A subunit (FXIII-A) leads to faster activation of FXIII, influences clot structure and provides a moderate protection against coronary artery disease. The effect of FXIII A subunit (FXIII-A) Val34Leu polymorphism on the risk of ischemic stroke (IS) has been investigated in a few...
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