Article
Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke.
Stroke - 1 Aug 2015
Hanscombe Ken B, Traylor Matthew, Hysi Pirro G, Bevan Stephen, Dichgans Martin, Rothwell Peter M, Worrall Bradford B, Seshadri Sudha, Sudlow Cathie, Williams Frances M K, Markus Hugh S, Lewis Cathryn M
Abstract excerpt
BACKGROUND AND PURPOSE: Abnormal coagulation has been implicated in the pathogenesis of ischemic stroke, but how this association is mediated and whether it differs between ischemic stroke subtypes is unknown. We determined the shared genetic risk between 14 coagulation factors and ischemic stroke and its subtypes. METHODS: Using genome-wide association study results for 14 coagulation factors from the...
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