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Article

Effect of ABC transporter expression and mutational status on survival rates of cancer patients.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2020

Kadioglu Onat, Saeed Mohamed E M, Munder Markus, Spuller Andreas, Greten Henry Johannes, Efferth Thomas

Abstract excerpt

ATP-binding cassette (ABC) transporters mediate multidrug resistance in cancer. In contrast to DNA single nucleotide polymorphisms in normal tissues, the role of mutations in tumors is unknown. Furthermore, the significance of their expression for prediction of chemoresistance and survival prognosis is still under debate. We investigated 18 tumors by RNA-sequencing. The mutation rate varied from 27,507 to 300885....

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Identifiers

PMID: 32932043
DOI: 10.1016/j.biopha.2020.110718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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