Inherited variation in the xenobiotic transporter pathway and survival of multiple myeloma patients.

doi:10.1111/bjh.15521

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Article

Inherited variation in the xenobiotic transporter pathway and survival of multiple myeloma patients.

British journal of haematology - 1 Nov 2018

Macauda Angelica, Castelli Eleonora, Buda Gabriele, Pelosini Matteo, Butrym Aleksandra, Watek Marzena, Kruszewski Marcin, Vangsted Annette Juul, Rymko Marcin, Jamroziak Krzysztof, Abildgaard Niels, Haastrup Eva Kannik, Mazur Grzegorz, Ríos Rafael, Jurczyszyn Artur, Zawirska Daria, Dudziński Marek, Raźny Małgorzata, Dutka Magdalena, Tomczak Waldemar, Suska Anna, Druzd-Sitek Agnieszka, Marques Herlander, Petrini Mario, Markiewicz Miroslaw, Martinez-Lopez Joaquin, Ebbesen Lene Hyldahl, Iskierka-Jażdżewska Elżbieta, Sainz Juan, Canzian Federico, Campa Daniele

Abstract excerpt

Over the past four decades, remarkable progress has been made in the treatment and prognosis of multiple myeloma (MM), although it remains an incurable disease. Chemotherapy resistance is a major hurdle for treatment efficacy. Drug resistance can be innate and so driven by genes involved in the drug metabolism pathways. We performed an association study of 71 germline variants within the major genes in those...

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Identifiers

PMID: 30079960
DOI: 10.1111/bjh.15521

Genes

ABCC2
ABCB1
ABCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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