Article
The role of altered microbial signaling via mutant NODs in intestinal inflammation.
Current opinion in gastroenterology - 1 Jan 2007
Rescigno Maria, Nieuwenhuis Edward Es
Abstract excerpt
PURPOSE OF REVIEW: Recently, a new class of intracellular pattern recognition receptors belonging to the family of nucleotide binding and oligomerization domain (NOD)-like receptors that includes NOD1, NOD2 and IPAF has been described. These proteins are involved in recognizing bacterial components or their degradation constituents that are delivered within the cytoplasm. In this review we will analyze the role...
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