Article
Hras1 VNTR alleles as susceptibility markers for lung cancer: relationship to microsatellite instability in tumors.
Anticancer research - 1 Jan 2000
Lindstedt B A, Ryberg D, Zienolddiny S, Khan H, Haugen A
Abstract excerpt
PURPOSE: To further evaluate lung cancer risk associated with rare Hras1 VNTR alleles and possible biological mechanisms. MATERIALS AND METHODS: The Hras1 VNTR was genotyped in 295 lung cancer patients and 500 healthy controls by PCR and high resolution electrophoresis. Microsatellite alterations were examined in 168 tumors by PCR and capillary electrophoresis. RESULTS: 35 Hras1 VNTR alleles were found, of which...
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