Article
Ha-ras hypervariable alleles in myelodysplasia.
Nature - 1 Jan 2000
Thein S L, Oscier D G, Flint J, Wainscoat J S
Abstract excerpt
The somatic mutation of one of the ras oncogenes is now considered to be a critical step in the pathogenesis of many tumours. Circumstantial evidence also suggests that some individuals may be genetically predisposed to malignancy and a general method used to analyse such disease susceptibility i...
Topics
- Alleles
- DNA
- DNA Restriction Enzymes
- Genetic Variation
- Humans
- Leukocytes
- Mutation
- Myelodysplastic Syndromes
- Oncogenes
- Reference Values