Article
On the nature of enduring modifications induced in cells and organisms.
The American journal of physiology - 1 Feb 1990
Rubin H
Abstract excerpt
The clarity of Mendelian genetics and the elegance of the molecular mechanisms of replication and readout of DNA have tended to obscure a solid body of evidence demonstrating that nongenetic, enduring modifications can be induced in the behavior of cells, modifications that continue to be expressed for many divisions after withdrawal of the inducing stimulus. The most prosaic case is the differentiated state of...
Topics
- Animals
- Bacteria
- Bacterial Physiological Phenomena
- Cell Physiological Phenomena
- Cells, Cultured
- DNA
- Eukaryota
- Models, Biological
- Mutation
- Neoplasms, Experimental
- Plant Physiological Phenomena