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Article

The significance of biological heterogeneity.

Cancer metastasis reviews - 1 Jul 1990

Rubin H

Abstract excerpt

Heterogeneity of expression for a variety of characteristics is found among malignant cells in the organism and in culture. Normal cells are relatively uniform when organized in a tissue, but become heterogeneous for many characteristics when they are dispersed and grown in monolayer culture. The heterogenizing effect of growth in culture indicates that the morphology and behavior of normal cells is ordered by...

Topics

Animals
Eukaryotic Cells
Genetic Variation
Humans
Neoplasms
Phenotype
Prokaryotic Cells

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2208565
DOI: 10.1007/BF00047585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2208565-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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