Article
Significance of linkage disequilibrium heterogeneous patterns in the 21q22.3 region for mapping 21 trisomy individuals.
Genetics and molecular research : GMR - 8 Aug 2013
Valle Y, Padilla-Gutiérrez J R, Quintero-Ramos A, García-González I J, Rivas F
Abstract excerpt
Recombination patterns can be indirectly inferred by means of linkage disequilibrium (LD) estimates, since LD is negatively correlated with genetic distance. However, LD does not necessarily have absolute correspondence with genetic distance. We estimated LD at 5 loci located in the 21q22.3 regio...
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