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Characterization of mutations and sequence variants in the D21S11 locus by next generation sequencing.

Forensic science international. Genetics - 1 Jan 2014

Rockenbauer Eszter, Hansen Stine, Mikkelsen Martin, Børsting Claus, Morling Niels

Abstract excerpt

We sequenced the D21S11 locus in 77 individuals from Danish paternity cases using 454 FLX next generation sequencing (NGS) technology. All samples were also typed with the AmpFlSTR Profiler Plus or the AmpFlSTR Identifiler PCR Amplification kits as part of paternity investigations. In 18 of the confirmed trios, a genetic inconsistency was observed between one of the parents and the child at the D21S11 locus. NGS...

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PMID: 24315591
DOI: 10.1016/j.fsigen.2013.06.011

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