Article
Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population.
American journal of human genetics - 1 May 1994
Peral B, Ward C J, San Millán J L, Thomas S, Stallings R L, Moreno F, Harris P C
Abstract excerpt
Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three highly polymorphic microsatellites (SM6, CW3, and CW2) and an RFLP marker (BLu24)--are described for the first time in this report. Overall the results reveal many different haplotypes on the disease-carrying...
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