Article
Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population.
American journal of human genetics - 1 May 1994
Peral B, Ward C J, San Millán J L, Thomas S, Stallings R L, Moreno F, Harris P C
Abstract excerpt
Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three highly polymorphic microsatellites (SM6, CW3, and CW2) and an RFLP marker (BLu24)--are describ...
Topics
- Alleles
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 16
- DNA Primers
- DNA, Satellite
- Genetic Markers
- Genetic Variation
- Haplotypes
- Humans
- Linkage Disequilibrium
- Molecular Sequence Data
- Polycystic Kidney, Autosomal Dominant
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Repetitive Sequences, Nucleic Acid
- Spain