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Article

Recurrent trisomy 21: four cases in three generations

31 Aug 2005

Abstract excerpt

Recurrent trisomy 21: four cases in three generations. While gonadal mosaicism can lead to recurrence of trisomy 21 (T21) for a single couple, the recurrence of free T21 in multiple members of a single pedigree has rarely been reported. We present an unusual pedigree with four cases of Down syndrome (DS) with free T21 were born to four separate women related through three generations of one family. The mothers...

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Identifiers

PMID: 16207210
DOI: 10.1111/j.1399-0004.2005.00512.x

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