Article
Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma.
BMC medical genetics - 24 Sept 2013
Senses Kerem M, Gonen Mithat, Barutcu Ahmet R, Kalaylioglu Zeynep, Isbilen Murat, Konu Ozlen, Chen Yao T, Altorki Nasser K, Gure Ali O
Abstract excerpt
BACKGROUND: Tumor-specific, coordinate expression of cancer-testis (CT) genes, mapping to the X chromosome, is observed in more than 60% of non-small cell lung cancer (NSCLC) patients. Although CT gene expression has been unequivocally related to DNA demethylation of promoter regions, the underly...
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