Article
The influence of methylenetetrahydrofolate reductase and thymidylate synthetase gene polymorphisms on lung adenocarcinoma occurrence.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Cavic Milena, Krivokuca Ana, Spasic Jelena, Brotto Ksenija, Malisic Emina, Radosavljevic Davorin, Radulovic Sinisa, Jankovic Radmila
Abstract excerpt
PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthetase (TYMS) are suggested as risk factors for lung cancer. The purpose of this study was to analyze the association of MTHFR C677T polymorphism and variable number tandem repeat 2R/3R and single nucleotide polymorphism G>C in the 3R allele of the TYMS gene with lung adenocarcinoma. METHODS: A case-control study including lung...
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