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Article

Prevalence of PALB2 mutation c.509_510delGA in unselected breast cancer patients from Central and Eastern Europe.

Familial cancer - 1 Jun 2014

Noskowicz Monika, Bogdanova Natalia, Bermisheva Marina, Takhirova Zalina, Antonenkova Natalia, Khusnutdinova Elza, Bremer Michael, Christiansen Hans, Park-Simon Tjoung-Won, Hillemanns Peter, Dörk Thilo

Abstract excerpt

Inherited mutations in PALB2 are known to be associated with increased breast cancer risk. We aimed to investigate the prevalence and risk association of a recurrent PALB2 mutation, c.509_510delGA, among 3,924 unselected breast cancer patients from Belarus, Russia or Germany. High-resolution melting analyses and direct sequencing identified the c.509_510delGA allele in 3/1,008 (0.3 %) German breast cancer...

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Identifiers

PMID: 24061862
DOI: 10.1007/s10689-013-9684-1

Genes

PALB2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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