Article
Mutation analysis of PALB2 gene in French breast cancer families.
Breast cancer research and treatment - 1 Dec 2015
Damiola Francesca, Schultz Inès, Barjhoux Laure, Sornin Valérie, Dondon Marie-Gabrielle, Eon-Marchais Séverine, Marcou Morgane, Caron Olivier, Gauthier-Villars Marion, de Pauw Antoine, Luporsi Elisabeth, Berthet Pascaline, Delnatte Capucine, Bonadona Valérie, Maugard Christine, Pujol Pascal, Lasset Christine, Longy Michel, Bignon Yves-Jean, Fricker Jean-Pierre, Andrieu Nadine, Sinilnikova Olga M, Stoppa-Lyonnet Dominique, Mazoyer Sylvie, Muller Danièle
Abstract excerpt
Several population-based and family-based studies have demonstrated that germline mutations of the PALB2 gene (Partner and Localizer of BRCA2) are associated with an increased risk of breast cancer. Distinct mutation frequencies and spectrums have been described depending on the population studied. Here we describe the first complete PALB2 coding sequence screening in the French population. We screened the...
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