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Article

Egr2 and Egr3 are the unique regulators for systemic autoimmunity

1 Apr 2013

Abstract excerpt

Systemic autoimmunity is characterized by widespread inflammation, autoantibody production and immune complex deposition. The regulatory mechanisms for the systemic autoimmunity are not fully understood. A paper by Li et al. revealed that Egr2 and Egr3, transcription factors required for T-cell anergy, are the regulators for systemic autoimmune disease. They showed evidence that Egr2 and Egr3 control cytokine...

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Share to Cytokine Signaling Pathways and Interactions
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PMID: 24058814
DOI: 10.4161/jkst.23952

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