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Article

Autoimmune polyglandular syndromes.

Nature reviews. Endocrinology - 1 May 2010

Michels Aaron W, Gottlieb Peter A

Abstract excerpt

The autoimmune polyglandular syndromes-a group of syndromes comprising a combination of endocrine and nonendocrine autoimmune diseases-differ in their component diseases and in the immunologic features of their pathogenesis. One of the three main syndromes, type 1 autoimmune polyglandular syndrome (APS-1), has a unique pathogenic mechanism owing to mutations in the autoimmune regulator (AIRE) gene, which results...

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Identifiers

PMID: 20309000
DOI: 10.1038/nrendo.2010.40

Genes

AIRE
FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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