Article
The molecular basis of immune regulation in autoimmunity.
Clinical science (London, England : 1979) - 16 Jan 2018
Yang Shu-Han, Gao Cai-Yue, Li Liang, Chang Christopher, Leung Patrick S C, Gershwin M Eric, Lian Zhe-Xiong
Abstract excerpt
Autoimmune diseases can be triggered and modulated by various molecular and cellular characteristics. The mechanisms of autoimmunity and the pathogenesis of autoimmune diseases have been investigated for several decades. It is well accepted that autoimmunity is caused by dysregulated/dysfunctional immune susceptible genes and environmental factors. There are multiple physiological mechanisms that regulate and...
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