Research progress of SOCS in autoimmune diseases: mechanisms and therapeutic implications

Abstract excerpt

Suppressor of cytokine signaling (SOCS) is a family of regulatory factors whose expression can be induced by various cytokines, growth factors, and hormones. Autoimmune diseases, chronic inflammatory conditions caused by abnormal immune responses, involve overactive T-cells and B-cells, excessive autoantibody production, and damage to multiple organs and systems. The pathogenic mechanisms of autoimmune diseases...

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