Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GSTCD and INTS12 Regulation and Expression in the Human Lung

18 Sept 2013

Abstract excerpt

Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a region on 4q24 containing two oppositely transcribed genes: glutathione S-transferase, C-terminal domain containing (GSTCD) and integrator complex subunit 12 (INTS12). Both genes were found to be expressed in a range of human airway cell types. The promoter regions and transcription...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Glutathione Transferases and Polymorphisms
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24058608
DOI: 10.1371/journal.pone.0074630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GSTCD and INTS12 Regulation and Expression in the Human LungPMID 24058608Read ↗

Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways.Semantic proximity Read ↗

Breathing new life into the study of COPD with genes identified from genome-wide association studies.Semantic proximity Read ↗

Co-methylation analysis in lung tissue identifies pathways for fetal origins of COPDSemantic proximity Read ↗

Lung Development Genes and Adult Lung Function.Semantic proximity Read ↗

Lung eQTLs to help reveal the molecular underpinnings of asthma.Semantic proximity Read ↗

Intrauterine Smoke Exposure, microRNA Expression during Human Lung Development, and Childhood AsthmaSemantic proximity Read ↗

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.Semantic proximity Read ↗

Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function.Semantic proximity Read ↗

eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes.Semantic proximity Read ↗

Genomic Locus Tagged by Lung Function GWAS SNV rs12477314 (2q37.3) Acts as a Regulatory Region for a Systemic Inflammatory Phenotype.Semantic proximity Read ↗

Genome-wide association study identifies five loci associated with lung function.Semantic proximity Read ↗

Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.