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Article

Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways.

BMC genomics - 23 Mar 2017

Kheirallah Alexander K, de Moor Cornelia H, Faiz Alen, Sayers Ian, Hall Ian P

Abstract excerpt

BACKGROUND: Genetic studies of human lung function and Chronic Obstructive Pulmonary Disease have identified a highly significant and reproducible signal on 4q24. It remains unclear which of the two candidate genes within this locus may regulate lung function: GSTCD, a gene with unknown function, and/or INTS12, a member of the Integrator Complex which is currently thought to mediate 3'end processing of small...

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Source

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Identifiers

PMID: 28335732
DOI: 10.1186/s12864-017-3628-3
PMCID: PMC5364626

Genes

INTS12
GSTCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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