Article
Robust and specific ratiometric biosensing using a copper-free clicked quantum dot-DNA aptamer sensor.
Nanoscale - 7 Nov 2013
Zhang Haiyan, Feng Guoqiang, Guo Yuan, Zhou Dejian
Abstract excerpt
We report herein the successful preparation of a compact and functional CdSe-ZnS core-shell quantum dot (QD)-DNA conjugate via highly efficient copper-free "click chemistry" (CFCC) between a dihydro-lipoic acid-polyethylene glycol-azide (DHLA-PEG-N3) capped QD and a cyclooctyne modified DNA. This represents an excellent balance between the requirements of high sensitivity, robustness and specificity for the...
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