Article
Toward a multiplexed solid-phase nucleic acid hybridization assay using quantum dots as donors in fluorescence resonance energy transfer.
Analytical chemistry - 15 May 2009
Algar W Russ, Krull Ulrich J
Abstract excerpt
Solid-phase assays using immobilized quantum dots (QDs) as donors in fluorescence resonance energy transfer (FRET) have been developed for the selective detection of nucleic acids. QDs were immobilized on optical fibers and conjugated with probe oligonucleotides. Hybridization with acceptor labeled target oligonucleotides generated FRET-sensitized acceptor fluorescence that was used as the analytical signal. A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
