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Article

A novel fluorescent sensor for mutational p53 DNA sequence detection based on click chemistry.

Biosensors & bioelectronics - 15 Mar 2013

Qiu Suyan, Li Xianghui, Xiong Wenming, Xie Lidan, Guo Longhua, Lin Zhenyu, Qiu Bin, Chen Guonan

Abstract excerpt

A novel fluorescent sensor for DNA sequence has been designed by taking advantages of copper nanoparticles (CuNPs) selectively formed on double stranded (ds) DNA template and Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. Copper(II) is derived from CuNPs which previously formed on the dsDNA template, and then copper(II) is reduced to copper(I) by ascorbate, which in turn induced CuAAC reaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23021842
DOI: 10.1016/j.bios.2012.08.065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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