Article
Epithelial-mesenchymal transition increases during the progression of in situ to invasive basal-like breast cancer.
Human pathology - 1 Nov 2013
Choi Yoomi, Lee Hee Jin, Jang Min Hye, Gwak Jae Moon, Lee Kyu Sang, Kim Eun Joo, Kim Hyun Jeong, Lee Hee Eun, Park So Yeon
Abstract excerpt
Epithelial-mesenchymal transition (EMT) is known to play an important role in breast cancer invasion and metastatic progression. However, the pattern of expression of EMT markers in the progression from in situ to invasive breast carcinoma is not clear. To investigate this, we performed immunohistochemical analyses of EMT markers (expression of vimentin, smooth muscle actin, osteonectin, and N-cadherin; loss of...
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