Article
Epithelial-mesenchymal transition in breast cancer correlates with high histological grade and triple-negative phenotype.
Histopathology - 1 May 2012
Jeong Hoiseon, Ryu Young-joon, An Jungsuk, Lee Youngseok, Kim Aeree
Abstract excerpt
AIMS: Epithelial-mesenchymal transition (EMT) is characterized by a loss of epithelial nature and the acquisition of a mesenchymal form. The aim of this study was to assess the role of EMT in human mammary carcinogenesis, by performing immunohistochemical studies of EMT markers with tissue microarrays. METHODS AND RESULTS: A total of 492 cases were evaluated and classified as hormone receptor (HR)-positive type,...
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