Article
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype.
Cancer research - 15 Feb 2008
Sarrió David, Rodriguez-Pinilla Socorro María, Hardisson David, Cano Amparo, Moreno-Bueno Gema, Palacios José
Abstract excerpt
Epithelial-mesenchymal transition (EMT) is defined by the loss of epithelial characteristics and the acquisition of a mesenchymal phenotype. In carcinoma cells, EMT can be associated with increased aggressiveness, and invasive and metastatic potential. To assess the occurrence of EMT in human breast tumors, we conducted a tissue microarray-based immunohistochemical study in 479 invasive breast carcinomas and 12...
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