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P-Cadherin Linking Breast Cancer Stem Cells and Invasion: A Promising Marker to Identify an â€œIntermediate/Metastableâ€ EMT State

5 Jan 2015

Abstract excerpt

Epithelial-mesenchymal transition (also known as EMT) is a fundamental mechanism occurring during embryonic development and tissue differentiation, being also crucial for cancer progression. Actually, the EMT program contributes to the dissemination of cancer cells from solid tumors and to the formation of micro-metastasis that subsequently develop into clinically detectable metastases. Besides being a process...

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PMID: 25601904
DOI: 10.3389/fonc.2014.00371

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