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Article

IGKC and FcγR genotypes and humoral immunity to HER2 in breast cancer.

Immunobiology - 1 Feb 2014

Pandey Janardan P, Kistner-Griffin Emily, Black Laurel, Namboodiri Aryan M, Iwasaki Motoki, Kasuga Yoshio, Hamada Gerson S, Tsugane Shoichiro

Abstract excerpt

Immunoglobulin κ constant (IGKC) gene has recently been identified as a strong prognostic marker in several human solid tumors, including breast cancer. Although the mechanisms underlying the IGKC signature are not yet known, identification of tumor-infiltrating plasma cells as the source of IGKC expression strongly suggests a role for humoral immunity in breast cancer progression. The primary aim of the present...

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Source

Identifiers

PMID: 24054945
DOI: 10.1016/j.imbio.2013.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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