Article
IgG and FcγR genotypes and humoral immunity to mucin 1 in prostate cancer.
Human immunology - 1 Aug 2013
Pandey Janardan P, Namboodiri Aryan M, Kistner-Griffin Emily
Abstract excerpt
Immunoglobulin GM and KM allotypes-hereditary antigenic determinants of γ and κ chains, respectively-and Fcγ receptor IIa (FcγRIIa) and FcγRIIIa genes are associated with the immunobiology of several malignant diseases, but their role in humoral immunity to the tumor-associated antigen mucin 1 (MUC1) in prostate cancer has not been examined. This investigation aimed to determine whether these genes-individually...
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