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Article

IGHG, IGKC, and FCGR genes and endogenous antibody responses to GARP in patients with breast cancer and matched controls.

Human immunology - 1 Aug 2018

Pandey Janardan P, Namboodiri Aryan M, Armeson Kent E, Iwasaki Motoki, Kasuga Yoshio, Hamada Gerson S, Tsugane Shoichiro

Abstract excerpt

Glycoprotein-A repetitions predominant (GARP) is a transmembrane protein that is highly expressed in breast cancer. Its overexpression correlates with worse survival, and antibodies to GARP appear to play a protective role in a mouse model. No large-scale studies of immunity to GARP in humans have yet been undertaken. In this investigation, using a large multiethnic cohort (1738 subjects), we aimed to determine...

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Share to Antibody Formation
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunoglobulin G

Share to Immunoglobulin Gm Allotypes

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Share to Receptors, IgG

Source

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Identifiers

PMID: 29879453
DOI: 10.1016/j.humimm.2018.06.001
PMCID: PMC6063529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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