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Genetic markers of immunoglobulin G and susceptibility to breast cancer.

Human immunology - 1 Nov 2012

Pandey Janardan P, Kistner-Griffin Emily, Iwasaki Motoki, Bu Shizhong, Deepe Ray, Black Laurel, Kasuga Yoshio, Hamada Gerson S, Tsugane Shoichiro

Abstract excerpt

Immunoglobulin GM allotypes, antigenic determinants of γ chains, are encoded by three very closely linked codominant genes on chromosome 14q32. Particular GM alleles/haplotypes are associated with antibody responses to certain tumor antigens and contribute to the cytotoxicity of breast cancer cells, but their possible role in susceptibility to this malignancy has not been adequately examined. Using a matched...

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Identifiers

PMID: 22884983
DOI: 10.1016/j.humimm.2012.07.340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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