Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Racially restricted contribution of immunoglobulin Fcγ and Fcγ receptor genotypes to humoral immunity to human epidermal growth factor receptor 2 in breast cancer.

Clinical and experimental immunology - 1 Mar 2013

Pandey J P, Namboodiri A M, Kistner-Griffin E, Iwasaki M, Kasuga Y, Hamada G S, Tsugane S

Abstract excerpt

Tumour-associated antigen human epidermal growth factor receptor 2 (HER2) is over-expressed in 25-30% of breast cancer patients and is associated with poor prognosis. Naturally occurring anti-HER2 antibody responses have been described in patients with HER2 over-expressing tumours. There is significant interindividual variability in antibody responsiveness, but the host genetic factors responsible for this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black People
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Humoral

Share to Immunoglobulin Gm Allotypes

Share to Immunotherapy

Share to Racial Groups

Share to Receptor, ErbB-2

Share to Receptors, IgG

Source

Open in PubMed Open full text

Identifiers

PMID: 23379433
DOI: 10.1111/cei.12018
PMCID: PMC3569534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Racially restricted contribution of immunoglobulin Fcγ and Fcγ receptor genotypes to humoral immunity to human epidermal growth factor receptor 2 in breast cancer.PMID 23379433Read ↗

Genetic regulation of antibody responses to human epidermal growth factor receptor 2 in breast cancer.Semantic proximity Read ↗

IGHG, IGKC, and FCGR genes and endogenous antibody responses to GARP in patients with breast cancer and matched controls.Semantic proximity Read ↗

Genetic markers of immunoglobulin G and susceptibility to breast cancer.Semantic proximity Read ↗

Endogenous antibody responsiveness to epidermal growth factor receptor is associated with immunoglobulin allotypes and overall survival of patients with glioblastoma.Semantic proximity Read ↗

IGKC and FcγR genotypes and humoral immunity to HER2 in breast cancer.Semantic proximity Read ↗

Endogenous antibody responses to mucin 1 in a large multiethnic cohort of patients with breast cancer and healthy controls: Role of immunoglobulin and Fcγ receptor genes.Semantic proximity Read ↗

Immunoglobulin GM (γ marker) allotypes and their role in immune response and disease susceptibility.Semantic proximity Read ↗

Differential inhibition of trastuzumab- and cetuximab-induced cytotoxicity of cancer cells by immunoglobulin G1 expressing different GM allotypes.Semantic proximity Read ↗

Genetic markers of immunoglobulin G and immunity to cytomegalovirus in patients with breast cancer.Semantic proximity Read ↗

Immunoglobulin genes influence the magnitude of humoral immunity to cytomegalovirus glycoprotein B.Semantic proximity Read ↗

Human immunoglobulin constant heavy G chain (IGHG) (Fcγ) (GM) genes, defining innate variants of IgG molecules and B cells, have impact on disease and therapy.Semantic proximity Read ↗

A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.